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Actinin-α1 rabbit pAb2

簡要描述:SourceRabbitApplicationsWB

  • 產品型號:
  • 廠商性質:生產廠家
  • 更新時間:2025-10-16
  • 訪  問  量:229

詳細介紹

  • Source

    Rabbit

  • Applications

    WB,IHC

  • Reactivity

    Mouse,Rat

  • Dilution

    WB: 1:1000-2000 IHC: 1:200-500

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Actinin-α1 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Recombinant Protein of Actinin-α1

  • Uniprot No

    P12814

  • Alternative names

    ACTN1; Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1

  • Form

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    actinin alpha 1(ACTN1) Homo sapiens Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • Other

    ACTN1, Alpha-actinin-1

  • Concentration

    1 mg/ml

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